Ursodeoxycholic acid diminishes Fas-ligand-induced apoptosis in mouse hepatocytes

Regulation of Fas Ligand-Induced Apoptosis

Ascorbic Acid Diminishes Developmental Damages Induced by High Glucose in Mouse Preimplantation Emberyos in vitro

The Mouse Cell Surface Protein Toso Regulates Fas/fas- Ligand Induced Apoptosis through Its Binding to Fadd *

THE MOUSE CELL SURFACE PROTEIN TOSO REGULATES FAS/FASLIGAND INDUCED APOPTOSIS THROUGH ITS BINDING TO FADD * Yahui Song and Chaim O. Jacob From the Department of Medicine and Molecular Microbiology and Immunology, University of Southern California School of Medicine, Los Angeles, CA 90089 Running title: Role of TOSO in apoptosis Address correspondence to: Chaim O. Jacob, Department of Medicine, ...

Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids

Activation of T cell hybridomas induces a G1/S cell cycle block and apoptosis. We isolated a variant of the 2B4.11 T cell hybridoma that, when activated via the TCR, produced IL-2 and underwent growth inhibition but did not die. Analysis of a variety of cell surface molecules revealed that the variant cell line, termed VD1, expressed very low levels of Fas compared to the wild type cells. Unlik...

Fas/Fas ligand interactions are involved in ultraviolet-B-induced human lymphocyte apoptosis.

We wondered whether the apoptosis known to occur after UV-B irradiation might involve the Fas/Fas ligand (FasL) signaling pathway. We exposed PBLs from normal individuals, and also the Jurkat (E6-1) and U937 cell lines, to graded doses of UV-B irradiation and observed a prompt and marked increase in Fas expression at doses as low as 0.5 mJ/cm2. Increased Fas expression did not require new prote...